The Thyroid and Vitamin B1
What is Vitamin B1?
- Definition: Vitamin B1, also known as thiamine, is a water-soluble vitamin essential for energy metabolism and the proper functioning of the nervous system. It is one of the B-complex vitamins. 
- Origin: The body cannot produce thiamine, so it must be obtained from dietary sources or supplements. 
What types of Vitamin B1 are there and what do they do?
- Natural Forms: Thiamine exists in food primarily as thiamine pyrophosphate (TPP), the active form of the vitamin. 
- Synthetic Forms: - Thiamine hydrochloride and thiamine mononitrate are used in supplements and fortified foods. 
- Benfotiamine: A fat-soluble derivative often used for diabetic complications. 
 
- Functions: All forms play a role in carbohydrate metabolism, energy production, and nervous system health. 
Daily Requirements for Vitamin B1 in all demographics
- Infants (0-6 months): 0.2 mg/day 
- Children (1-3 years): 0.5 mg/day 
- Adolescents (9-13 years): 0.9 mg/day 
- Adults (18+ years): 1.1 mg/day for women, 1.2 mg/day for men 
- Pregnancy and Lactation: 1.4 mg/day to support increased metabolic needs. 
What does Vitamin B1 do in our body?
- Energy Production: Acts as a coenzyme in the breakdown of glucose for ATP production. 
- Nerve Function: Essential for the synthesis of neurotransmitters, promoting nerve signal transmission. 
- Muscle Contraction: Supports proper muscular function by aiding in nerve-muscle coordination. 
Symptoms of Vitamin B1 Deficiency
- Mild Deficiency: Fatigue, irritability, poor memory, and muscle weakness. 
- Severe Deficiency: - Beriberi is characterized by muscle wasting, weakness, and cardiovascular issues. 
- Wernicke-Korsakoff Syndrome: A neurological disorder caused by chronic deficiency, common in alcoholics. 
 
What does Vitamin B1 do for our thyroid pathway?
- Energy for Thyroid Function: Enhances energy metabolism, which is crucial for thyroid hormone production and utilization. 
- Oxidative Stress Reduction: Protects thyroid cells from oxidative damage. 
- Immune Support: Strengthens the immune system, reducing autoimmune attacks on the thyroid. 
What does Vitamin B1 do for our Liver?
- Detoxification: Assists the liver in metabolizing toxins through enzymatic processes. 
- Energy Supply: Supports carbohydrate metabolism in liver cells, maintaining optimal liver function. 
- Fat Metabolism: Helps prevent fatty liver by aiding in the proper breakdown of fats. 
What does Vitamin B1 do for our gut?
- Digestion Support: Enhances carbohydrate digestion and absorption. 
- Gut-Brain Axis: Promotes healthy gut microbiota, indirectly supporting mental health. 
- Motility Regulation: Improves gut motility, reducing the risk of constipation. 
Physical Ailments that affect Vitamin B1
- Alcoholism: Interferes with absorption and storage of thiamine. 
- Diabetes: Increased excretion of thiamine in urine, leading to deficiency. 
- Celiac Disease: Impairs absorption of thiamine due to intestinal damage. 
Food that impacts Vitamin B1
- Thiaminases: Found in raw fish and shellfish, these enzymes break down thiamine. 
- Anti-nutrients: Polyphenols in tea and coffee can reduce absorption. 
Medications that Impact Vitamin B1
- Diuretics: Increase urinary excretion of thiamine. 
- Antibiotics: Prolonged use can disrupt gut flora, reducing thiamine synthesis. 
- Chemotherapy Drugs: Can interfere with thiamine metabolism. 
Natural Supplements that negatively impact Vitamin B1
- High-dose Vitamin C: May degrade thiamine in large quantities. 
- Calcium Supplements: Excess calcium can impair thiamine absorption. 
Heavy Metals that Impact Vitamin B1
- Lead and Mercury: Deplete thiamine stores and disrupt enzyme activity. 
- Cadmium: Interferes with thiamine-dependent enzymatic reactions. 
Testing for Vitamin B1
- Blood Tests: Measure thiamine levels directly in the blood. 
- Erythrocyte Transketolase Activity: Assesses enzyme activity dependent on thiamine. 
Nutrients Required for Vitamin B1 Absorption
- Magnesium: Aids in the activation of thiamine to its coenzyme form. 
- Zinc: Supports thiamine-dependent enzymatic reactions. 
Foods high in Vitamin B1
- Whole Grains: Brown rice, oats, and wheat germ. 
- Meats: Pork, liver, and chicken. 
- Legumes: Lentils, black beans, and peas. 
- Seeds and Nuts: Sunflower seeds and flaxseeds. 
A Recipe high in Vitamin B1
- Thiamine Boosting Stir-Fry: Combine pork strips, brown rice, and a mix of green vegetables like broccoli and spinach. Use sesame seeds as a topping for extra nutrients. 
Other Random Information about Vitamin B1
- Heat Sensitivity: Thiamine is destroyed by prolonged cooking or high heat. 
- Storage in the Body: Thiamine has a short half-life, so consistent dietary intake is essential. 
- Mental Health: Adequate thiamine levels are linked to reduced anxiety and better cognitive performance. 
Disclaimer: The information provided in this article is for educational purposes only and is not intended to diagnose, treat, or cure any medical condition. Always consult with a qualified healthcare professional before making any changes to your diet, lifestyle, or treatment plan. Individual needs may vary, and what works for one person may not be suitable for another.
 
                        